Just caught that bit from one of Jonathan Ian Matters' rants, "people pissing me off" which can be found here.
I don't necessairely agree with that specific sentence, it simply managed to catch my attention. Paranoia hurts, you can't live your life paranoid, looking ove your shoulder wherever you go. You need not spend your life "condition white" either. It can be in your best interest to err on the safe side once in a while, to be carefull, to be suspicious, but all in good measure.
Thinking like a serial killer once in a while seems a bit of a stretch, it is a humorous sketch after all. Wired released an article recently concerning a security mindset of security professionals: thinking like a criminal.